Goat Secondary Antibodies
Cayman Chemical E3 Ligand-Linker Conjugate 3 (hydrochloride), Purity: ≥95%, CAS: 2245697-86-1, 50 mg
A PROTAC building block containing thalidomide; has been used in the synthesis of PROTACs for the degradation ALK and BET family of proteins with anticancer activity
Cayman Chemical E3 Ligand-Linker Conjugate 3 (hydrochloride), Purity: ≥95%, CAS: 2245697-86-1, 10 mg
A PROTAC building block containing thalidomide; has been used in the synthesis of PROTACs for the degradation ALK and BET family of proteins with anticancer activity
Cayman Chemical Sorafenib (tosylate), Purity: ≥98%, CAS: 475207-59-1, 5 g
A multi-kinase inhibitor; inhibits Raf-1 and B-RAF (IC50s = 6 and 22 µM, respectively); inhibits VEGFR2, VEGFR3, PDGFRβ, FLT3, and c-Kit (IC50s = 90, 15, 20, 57, and 58 nM, respectively); selective for these kinases over 12 other kinases (IC50s = >10 µM for all); inhibits proliferation of PLC/PRF/5 and HepG2 cells (IC50s = 6.3 and 4.5 µM, respectively); inhibits tumor growth in a PLC/PRF/5 mouse xenograft model at 30 mg/kg; induces ferroptotic cell death in HT-1080 fibrosarcoma cells at 10 µM but not in a variety of other cancer cell lines; inhibits HCV replication in Huh7.5 cells (IC50 = 7.2 µM)
Cayman Chemical Clidinium (bromide), Purity: ≥98%, CAS: 3485-62-9, 1 g
A gastrointestinal muscarinic receptor antagonist (Ki = 3 nM against [3H]quinuclidinyl benzilate binding in rat colonic enterocytes); a dose of 1 mg/kg slows intestinal transit and induces constipation in mice; induces serum hyperammonemia; decreases clonic, myoclonic, and tonic seizure thresholds in a murine pentylenetetrazole-induced epilepsy model
Cayman Chemical Goat ntIMouse IgE SureLIght
Goat anti-Mouse IgE conjugated to SureLight™ R-PE Antibody: Goat polyclonal anti-Mouse IgE Isotype: IgE Dye: SureLight™ R-phycoerythrin Excitation max. λ: 565>498 nm Emission max. λ: 578 nm Uses: Flow cytometry, Fluorescence-activated cell sorting, Luminex, and Protein Microarrays
Cayman Chemical all-cis-4,7,10,13,16-Docosapentaenoic Acid ethyl ester, Purity: ≥98%, CAS: 142828-42-0, 250 mg
A derivative of DPA often used in formulations designed as dietary supplements
Cayman Chemical Paromomycin (sulfate), Purity: ≥98%, CAS: 1263-89-4, 5 g
An aminoglycoside antibiotic; effective against Gram-negative and Gram-positive bacteria (MICs = 0.08-3.9 µg/ml); antiprotozoal; decreases the parasite burden of mice infected with L. tropica when administered at a dose of 50 mg/kg and 15 mg/kg, through intramuscular or intralesional routes, respectively; binds to the tRNA decoding A site of the 16S ribosomal RNA in bacteria; inhibits protein synthesis
Cayman Chemical Dicloxacillin (sodium salt hydrate), Purity: ≥98%, CAS: 13412-64-1, 1 g
A semisynthetic penicillin antibiotic; has activity against Gram-positive bacteria (MICs = 0.02-0.24 μg/ml for S. pyogenes, S. aureus, and D. pneumoniae); protective against S. pyogenes, S. aureus, and D. pneumoniae infections in mice when administered subcutaneously or orally (PD50s = 12-185 and 41-280 mg/kg, respectively)
Cayman Chemical Nateglinide, Purity: ≥98%, CAS: 105816-04-4, 1 g
A hygoglycemic agent; induces insulin and somatostatin release from perfused rat pancreas from 0.03-3 μM; increases intracellular calcium levels in isolated rat pancreatic β cells at 3 μM; reduces blood glucose levels by 20% in fasted mice at 1.6 mg/kg orally; decreases blood glucose levels in an oral glucose tolerance test in normal rats, genetically diabetic KK mice, and an STZ-induced rat models of diabetess
Cayman Chemical Carbinoxamine (maleate), Purity: ≥98%, CAS: 3505-38-2, 1 g
A histamine H1 receptor antagonist (Ki = 2.3 nM) and first generation antihistamine; competes with [3H]diltiazem for binding to the benzothiazepine site on rat cardiomyocytes (Ki = 1.08 nM); decreases negative inotropic activity in isolated guinea pig left atria by 76% (EC50 = 250 nM); decreases negative chronotropic activity in guinea pig spontaneously beating isolated right atria by 48%
Cayman Chemical Medroxyprogesterone 17-acetate, Purity: ≥98%, CAS: 71-58-9, 1 g
A synthetic progestogen; prevents fertilization and increases the rate of transport of eggs from the fallopian tubes to the uterus in female ferrets when administered prior to ovulation; reversibly blocks ovulation in rats when injected on the last day of diestrus; has anti-androgenic activity in rats, decreasing plasma testosterone levels via induction of hepatic testosterone reductase activity; inhibits production of IFN-γ by CD2/CD3/CD28-stimulated PBMCs and extends the survival of rabbit skin allografts
Cayman Chemical Dicyclomine (hydrochloride), Purity: ≥98%, CAS: 67-92-5, 500 mg
A M1 and M2 muscarinic acetylcholine receptor antagonist (Kis = 3.16 and 44.7 nM, respectively); inhibits carbachol-stimulated inositol phosphate accumulation in guinea pig cortex (Ki = 12 nM; pA2 = 7.88); inhibits potassium-induced contraction of ileum, colon, and duodenum in anesthetized rats by 21.85, 30.81, and 37.86%, respectively (10 mg/kg, i.v.)
Cayman Chemical Goat ntIHumn IgA SureLIght
Goat Anti-Human IgA conjugated to SureLight™ R-PE, 100μg Antibody: Goat polyclonal Anti-Human IgA Isotype: IgA Uses: Flow cytometry, Fluorescence-activated cell sorting, Luminex, and Protein Microarrays
Cayman Chemical Fluphenazine (hydrochloride), Purity: ≥95%, CAS: 146-56-5, 1 g
A D1 and D2 receptor antagonist (Kis = 5 and 0.63 nM, respectively); binds to histamine H1, serotonin 5-HT2A, and 5-HT2B receptors (Kis = 45, 17, and 82 nM, respectively); acts as an inverse agonist at H1 and 5-HT2A receptors; a typical antipsychotic compound that induces extrapyramidal symptoms in monkeys
Kingfisher Biotech Inc Ferret TNFSF15 Protein (Yeast, Endotoxin - Free) - 5 ug
The Ferret TNFSF15 yeast-derived recombinant protein is not tagged and is naturally endotoxin-free. The purity is greater than 98% as visualized by SDS-PAGE analysis. Ferret TNFSF15 applications are for cell culture, ELISA standard, and Western Blot Control. The Ferret TNFSF15 yeast-derived recombinant protein can be purchased in multiple sizes. Ferret TNFSF15 Specifications: (Molecular Weight: 20.1 kDa) (Amino Acid Sequence: SKGLEFGSSH QRAYASTGAG GDKPRAHLTV VRQSPTQSSK NQFPALHWEH ELGLAFTKNR MNYTNKFLVI PESGDYFVYS QVTFRGTKSE CGEIRQGSRP NKPDSIIVVI TKVTDSYPEP TQLLMGTKSV CEVGSNWFQP IYLGAMFSLQ EGDKLMVNVS DISLVDYTKE DKTFFGAFLL). For research use only. Made in the USA
